Considering automated driving, vehicle dynamics control systems are also a crucial aspect. Vehicle dynamics control systems serve as an important influence factor on safety and ride comfort. By reducing the driver’s responsibility through partially or fully automated driving functions, the occupants’ perception of safety and ride comfort changes. Both aspects are focused even more and have to be enhanced. In general, research on vehicle dynamics control systems is a field that has already been well researched. With regard to the mentioned aspects, however, a central control structure features sufficient potential by exploiting synergies. Furthermore, a predictive mode of operation can contribute to achieve these objectives, since the vehicle can act in a predictive manner instead of merely reacting. Consequently, this contribution presents a central predictive control system by means of a non-linear model-based predictive control algorithm. In this context, roll, self-steering and pitch behavior are considered as control objectives. The active roll stabilization demonstrates an excellent control quality with a root mean squared error of 7.6953×10−3 rad averaged over both validation maneuvers. Compared to a vehicle utilizing a conventional control approach combined with a skyhook damping, pitching movements are reduced by 19.75%. Furthermore, an understeering behavior is maintained, which corresponds to the self-steering behavior of the passive vehicle. In general, the central predictive control, thus, increases both ride comfort and safety in a holistic way.