So-called structural change is an ongoing process in the Ruhr area and will unquestionably remain so into the future. Meanwhile, a spatial as well as a chronological differentiation within the Ruhr area itself can be observed, which has been linked to a focus on content as well as on specialization. The logistics industry, being tightly connected to traffic infrastructure as a location factor, assumes a crucial role when it comes to the ever increasing needs of a globalized world economy and its ‚ondemand‘ services. In this context, it can be of significant importance both spatially and employment-wise for regional structural change to take place at single, preferred locations.