Nickelspeziesanalyse im Cytosol humaner intestinaler Gewebeproben mittels online-Kopplung von Kapillarelektrophorese und induktiv gekoppeltem Plasma-Massenspektrometer

This thesis deals with the nickelspecies-analysis in cytosol of human intestinal tissue. The aim was, to find the differences in nickelspecies between the cytosol of malignant and normal tissue of the same patient with CE/ICP-MS resp. SEC/ICP-MS coupling. The result was, that the area ratio of two nickelspecies in the cytosol of malignant tissue are significant higher than in the cytosol of normal tissue. Maybe the two nickelspecies can be an oncogenproduct.


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