Visual snow syndrome is probably not mediated by CGRP : A case series

Affiliation
Department of Neurology, Krankenhaus Lindenbrunn, Coppenbrügge, Germany
Evers, Stefan;
GND
132478552
LSF
55495
Affiliation
Department of Neurology, University of Essen, Germany
Holle-Lee, Dagny;
ORCID
0000-0003-4668-6098
Affiliation
Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Switzerland
Schankin, Christoph J.;
Affiliation
Department of Neurology, Charité Universitätsmedizin Berlin, Germany
Kull, Pia;
ORCID
0000-0001-9758-1494
Affiliation
Department of Neurology, Charité Universitätsmedizin Berlin, Germany
Raffaelli, Bianca

Background: Visual snow syndrome is a phenomenon for which no effective treatment is known. It is highly comorbid with migraine, therefore we performed a retrospective chart review of patients with visual snow syndrome treated with a monoclonal antibody against calcitonin gene related peptide or its receptor.

Findings: We enrolled 15 patients with visual snow syndrome who received at least once a monoclonal antibody against calcitonin gene related peptide or its receptor. None of the patients reported relief of visual snow syndrome whereas those patients with comorbid migraine reported a very good efficacy of the antibody against the migraine headache but not against the migraine aura.

Conclusion: The data suggest that visual snow syndrome is not mediated by calcitonin gene related peptide in a relevant way and that the calcitonin gene related peptide receptor is not involved in the network underlying the visual snow syndrome.

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Date Issued:
25.05.2022
URN:
urn:nbn:de:hbz:465-20230825-150220-7
DOI:
10.1177/03331024221099220
Language:
English
Type of Resource:
Text
Keywords:
Visual snow syndrome; migraine; aura; CGRP antibody
Collection:
E-Publications
Subject categories of the Deutsche Nationalbibliografie:
610 Medical sciences Medicine
Hosting institution:
Faculty of Medicine, Essen University Hospital, Clinic for Neurology
funding:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
Info on primary publication:

Evers S, Holle-Lee D, Schankin CJ, Kull P, Raffaelli B. Visual snow syndrome is probably not mediated by CGRP: A case series. Cephalalgia. 2022;42(11-12):1294-1298. doi:10.1177/03331024221099220

First published online May 25, 2022

version identification:
Version of Record / Verlagsversion

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© International Headache Society 2022

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