000K  utf8
1100  2024$c2024-03-21
1500  eng
2050  urn:nbn:de:hbz:465-20241230-154845-2
2051  10.1111/iwj.14824
3000  Moelleken, Maurice
3010  Benson, Sven
3010  Cyrek, Anna Ewa
3010  Dissemond, Joachim
3010  Krefting, Frederik
3010  Krimphove, Sebastian Heinrich
3010  Rammos, Christos
4000  How effective is simple mechanical wound debridement in reducing bacterial colonisation?$dResults of a prospective clinical study  [Moelleken, Maurice]
4209  Background and aims: Bacteria in wounds can lead to stagnation of wound healing as well as to local or even systemic wound infections up to potentially lethal sepsis. Consequently, the bacterial load should be reduced as part of wound treatment. Therefore, the efficacy of simple mechanical wound debridement should be investigated in terms of reducing bacterial colonisation. Patients and methods: Patients with acute or chronic wounds were assessed for bacterial colonisation with a fluorescence camera before and after mechanical wound debridement with sterile cotton pads. If bacterial colonisation persisted, a second, targeted wound debridement was performed. Results: A total of 151 patients, 68 (45.0%) men and 83 (55.0%) women were included in this study. The male mean age was 71.0 years and the female 65.1 years. By establishing a new analysis method for the image files, we could document that the bacterial colonised areas were distributed 21.9% on the wound surfaces, 60.5% on the wound edges (up to 0.5 cm) and 17.6% on the wound surroundings (up to 1.5 cm). One mechanical debridement achieved a significant reduction of bacterial colonised areas by an average of 29.6% in the wounds, 18.9% in the wound edges and 11.8% in the wound surroundings and was increased by performing it a second time. Conclusions: It has been shown that even a simple mechanical debridement with cotton pads can significantly reduce bacterial colonisation without relevant side effects. In particular, the wound edges were the areas that were often most contaminated with bacteria and should be included in the debridement with special attention. Since bacteria remain in wounds after mechanical debridement, it cannot replace antimicrobial therapy strategies, but offer a complementary strategy to improve wound care. Thus, it could be shown that simple mechanical debridement is effective in reducing bacterial load and should be integrated into a therapeutic approach to wounds whenever appropriate.
4950  https://doi.org/10.1111/iwj.14824$xR$3Volltext$534
4950  https://nbn-resolving.org/urn:nbn:de:hbz:465-20241230-154845-2$xR$3Volltext$534
4961  https://duepublico2.uni-due.de/receive/duepublico_mods_00082015
5051  610
5550  autofluorescence
5550  bacterial wound colonisation
5550  fluorescence camera
5550  wound
5550  wound healing