000K utf8 1100 2024$c2024-03-12 1500 eng 2050 urn:nbn:de:hbz:465-20240927-125945-3 2051 10.1002/open.202300282 3000 Feng, Huayang 3010 Buchholz, Sebastian 3010 Cantore, Miriam 3010 Fabrizi, Jonas 3010 Ferenz, Katja Bettina 3010 Garvin, Maria Davila 3010 Hermsen, Andrea 3010 Hillen, Eva 3010 Kirsten, Annika 3010 Linders, Jürgen 3010 Mayer, Christian 3010 Myszkowska, Sascha 3010 Uteschil, Florian 4000 Cross-linked Triblock Peptide Capsules as Potential Oxygen Carriers [Feng, Huayang] 4209 Perfluorodecalin (PFD)-filled capsules have been studied for over 15 years as artificial oxygen carriers. However, none of these capsules combines good biocompatibility, good mechanical stability and dispersion stability. Here we propose to use synthetic triblock peptides containing a central block of cysteine units as a cross-linking shell material for capsules with both good biocompatibility and stability. Together with outer aspartate units and inner phenylalanine units, the resulting amphiphilic triblock peptides can encapsulate PFD efficiently to prepare capsules with a suitable diameter, a certain mechanical strength, a large diffusion constant, fast gas exchange rates, and little cytotoxicity. Given the above advantages, these PFD-filled peptide capsules are very promising as potential artificial oxygen carriers. 4950 https://doi.org/10.1002/open.202300282$xR$3Volltext$534 4950 https://nbn-resolving.org/urn:nbn:de:hbz:465-20240927-125945-3$xR$3Volltext$534 4961 https://duepublico2.uni-due.de/receive/duepublico_mods_00082010 5051 540 5051 610