000K utf8 1100 2022$c2022-12-16 1500 eng 2050 urn:nbn:de:hbz:465-20230627-142426-7 2051 10.3390/s22249946 3000 Moll, Fabian 3010 Adermann, Jens 3010 Bonetto, Anna 3010 Dudda, Marcel 3010 Herten, Monika 3010 Kessel, Axel 3010 Stresow, Johanna 4000 Use of Robot-Assisted Gait Training in Pediatric Patients with Cerebral Palsy in an Inpatient Setting$dA Randomized Controlled Trial [Moll, Fabian] 4209 Robot-assisted gait training (RAGT) provides a task-based support of walking using exoskeletons. Evidence shows moderate, but positive effects in the therapy of patients with cerebral palsy (CP). This study investigates the impact of RAGT on walking speed and gait parameters in pediatric CP patients. Thirty subjects (male = 23; female = 7), with a mean age of 13.0 ± 2.5 (9–17) years, and with spastic CP, were recruited. The intervention group (n = 15) underwent six 20-minute RAGT sessions with the Hybrid Assistive Limb (HAL) during an 11-day hospital stay. Additionally, a therapy concept including physiotherapy, physician-performed manual medicine, massage and exercise therapy was provided. The control group (n = 15) was treated with the therapy concept only. The outcome was based on a 10-Metre Walking Test (10MWT), 6-Minute Walking Test (6MWT), Gross Motor Function Measure (GMFM-88) and lower extremities passive range of motion. The intervention group achieved a mean increase in walking speed in the 10MWT (self-selected walking speed SSW) of 5.5 s (p = 0.378). There were no significant differences between the groups in the 10MWT (max) (p = 0.123) and the 6MWT (p = 0.8). Changes in the GMFM (total) and in the dimension standing and walking, running and jumping (D + E) showed clinically relevant significant results (p = 0.002 and p = 0.046). RAGT as a supplement to an inpatient therapy stay appears to have a positive, yet not significant impact on the gait parameters of pediatric CP patients as well as motivating them to practice walking. Further studies with adapted study designs are needed to evaluate different influencing factors. 4950 https://doi.org/10.3390/s22249946$xR$3Volltext$534 4950 https://nbn-resolving.org/urn:nbn:de:hbz:465-20230627-142426-7$xR$3Volltext$534 4961 https://duepublico2.uni-due.de/receive/duepublico_mods_00078146 5051 610 5550 cerebral palsy 5550 exoskeleton device 5550 gait disorders neurologic 5550 hybrid assistive limb 5550 pediatrics 5550 robot-assisted gait training 5550 walking 5550 walk test