000K utf8 1100 2020$c2020-02-01 1500 eng 2050 urn:nbn:de:hbz:464-20210503-140422-9 2051 10.1177/2048872618762639 3000 Vafaie, Mehrshad 3010 Barth, Sebastian 3010 Darius, Harald 3010 Giannitsis, Evangelos 3010 Hailer, Birgit 3010 Haude, Michael 3010 Heusch, Gerd 3010 Hochadel, Matthias 3010 Katus, Hugo A. 3010 Maier, Lars S. 3010 Mudra, Harald 3010 Münzel, Thomas 3010 Schmitt, Claus 3010 Schumacher, Burghard 3010 Senges, Jochen 3010 Voigtländer, Thomas 4000 Guideline-adherence regarding critical time intervals in the German Chest Pain Unit registry [Vafaie, Mehrshad] 4209 Background: Since 2008, the German Cardiac Society certified 256 Chest Pain Units (CPUs). Little is known about adherence to recommended performance measures in patients with suspected acute coronary syndrome (ACS) presenting to CPUs. We investigated guideline-adherence regarding critical time intervals and selected performance measures in German Chest Pain Units. Methods: From 2008 to 2014, 23,804 consecutive patients with suspected ACS were prospectively enrolled in the Chest Pain Unit registry of the German Cardiac Society. Results: Median time from symptom onset to first medical contact was 2 h in patients with ST-elevation myocardial infarction (STEMI) and 4 h in patients with unstable angina and non-STEMI (NSTEMI). In patients with STEMI, median time from hospital admission to percutaneous coronary intervention (PCI) was 40 min and median time from first medical contact to PCI was 1 h 35 min. Primary PCI was performed in 94.7% of patients with STEMI, 70.0% of patients with NSTEMI and 37.4% of patients with unstable angina. PCI was performed during the first 24 h in 79.5% of patients with NSTEMI and the first 72 h in 89.0% of patients with unstable angina. Electrocardiograms were performed in 99.5% after a median of 6 min after admission and obtained within 10 min in 71%. Interestingly, 56.1% of patients were found to have non-ACS diagnoses, underlining the importance of access to additional diagnostic modalities including echocardiography, stress testing or computed tomography. Conclusions: Guideline-adherence regarding critical time intervals and primary PCI rates is good in German Chest Pain Units. More than half of patients admitted with suspected ACS had non-ACS diagnoses. Improvements in pre-hospital time delays through public awareness programmes are warranted. 4950 https://doi.org/10.1177/2048872618762639$xR$3Volltext$534 4950 https://nbn-resolving.org/urn:nbn:de:hbz:464-20210503-140422-9$xR$3Volltext$534 4961 https://duepublico2.uni-due.de/receive/duepublico_mods_00071725 5051 610 5550 Acute coronary syndrome 5550 Chest Pain Unit 5550 guideline-adherence 5550 time intervals