Value of DSA in the Diagnostic Workup of Pulsatile Tinnitus

Deuschl, Cornelius; Göricke, Sophia LSF; Gramsch, Carolin LSF; Özkan, Neriman LSF; Lehnerdt, Götz Frederik LSF; Kastrup, Oliver LSF; Ringelstein, Adrian LSF; Wanke, Isabel LSF; Forsting, Michael LSF; Schlamann, Marc U. LSF

Objectives
Pulsatile tinnitus (PT) is a rare complaint, but can be a symptom of life-threatening disease. It is often caused by vascular pathologies, e.g. dural arteriovenous fistula (dAVF), arteriovenous malformation (AVM) or vascularized tumors. The current diagnostic pathway includes clinical examination, cranial MRI and additional DSA. The aim of this study was to evaluate the diagnostic impact of DSA in the diagnostic workup of patients with PT in comparison to MRI alone.
Methods
Retrospectively, 54 consecutive patients with pulsatile tinnitus were evaluated. All patients had a diagnostic workup including cranial MRI and DSA. MRI examinations were blinded to the results of DSA and retrospectively analyzed in consensus by two experienced neuroradiologists. The MR-examinations were evaluated for each performed sequence separately: time-of-flight-angiography, ce-MRA, T2, ce-T1-sequence and ce-T1-sequence with fat saturation.
Results
37 of the 54 patients revealed a pathology explaining PT on MRI, which was detected by the readers in 100% and proofed by means of DSA. 24 dAVF, four paraganglioma, two AVM and seven more pathologies were described. All patients without pathology on MRI did also not show any pathology in DSA.
Conclusions
MR imaging is sufficient to exclude pathology in patients with pulsatile tinnitus.

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Deuschl, C., Göricke, S., Gramsch, C., Özkan, N., Lehnerdt, G.F., Kastrup, O., Ringelstein, A., Wanke, I., Forsting, M., Schlamann, M.U., 2016. Value of DSA in the Diagnostic Workup of Pulsatile Tinnitus. https://doi.org/10.1371/journal.pone.0117814
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